Cigarette smoke extracts and cadmium induce COX-2 expression through γ-secretase-mediated p38 MAPK activation in C6 astroglia cells

Exposure to cigarette smoke has been implicated in the progression of cerebrovascular and neurological disorders like stroke through inflammation and blood-brain barrier disruption. In this study, we investigated the signaling cascade activated by cigarette smoke extracts (CSE) and cadmium (Cd) resu...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Lim, Hyun Joung, Park, Jung Hyun, Jo, Chulman, Yoon, Keejung, Koh, Young Ho
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2019
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6386363/
https://ncbi.nlm.nih.gov/pubmed/30794693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0212749
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