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Rhodamine–Hoechst positional isomers for highly efficient staining of heterochromatin

Hoechst conjugates to fluorescent dyes are popular DNA stains for live-cell imaging, but the relationship between their structure and performance remains elusive. This study of carboxyrhodamine–Hoechst 33258 conjugates reveals that a minimal change in the attachment point of the dye has dramatic eff...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Bucevičius, Jonas, Keller-Findeisen, Jan, Gilat, Tanja, Hell, Stefan W., Lukinavičius, Gražvydas
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6385482/
https://ncbi.nlm.nih.gov/pubmed/30881625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc05082a
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