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Alectinib in the treatment of ALK-positive metastatic non-small cell lung cancer: clinical trial evidence and experience with a focus on brain metastases

Molecular profiling of metastatic nonsquamous non-small cell lung cancer (NSCLC) is required to guide the treatment strategy. Anaplastic lymphoma kinase (ALK) gene rearrangements are found in approximately 5% of lung adenocarcinomas and are associated with specific clinical features including a high...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Ther Adv Respir Dis
Hauptverfasser: Tomasini, Pascale, Egea, Julie, Souquet-Bressand, Maxime, Greillier, Laurent, Barlesi, Fabrice
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6385324/
https://ncbi.nlm.nih.gov/pubmed/30786826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1753466619831906
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