Angiomotin-p130 inhibits β-catenin stability by competing with Axin for binding to tankyrase in breast cancer

Growing evidence indicates that Angiomotin (Amot)-p130 and Amot-p80 have different physiological functions. We hypothesized that Amot-p130 is a tumor suppressor gene in breast cancer, in contrast with the canonical oncogenicity of Amot-p80 or total Amot. To clarify the role of Amot-p130 in breast ca...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Yang, Jiao, Zhang, Xiaoman, Chen, Zheling, Shen, Yanwei, Wang, Fan, Wang, Yaochun, Liu, Yu, Liu, Peijun, Yang, Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6385204/
https://ncbi.nlm.nih.gov/pubmed/30792381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1427-2
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