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Anti-inflammatory effect of afatinib (an EGFR-TKI) on OGD-induced neuroinflammation
Activated epidermal growth factor receptor (EGFR) has been proposed in the pathophysiology of neurodegenerative diseases. In the present study, the anti-inflammatory effect of afatinib, an EGFR-tyrosine kinase inhibitor (EGFR-TKIs) was investigated using CTX-TNA2 cells and primary cultured astrocyte...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6385176/ https://ncbi.nlm.nih.gov/pubmed/30792526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-38676-7 |
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