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Relationships among KRAS mutation status, expression of RAS pathway signaling molecules, and clinicopathological features and prognosis of patients with colorectal cancer

BACKGROUND: The RAS/RAF/MEK/ERK and PI3K/AKT/mTOR signaling pathways all belong to mitogen-activated protein kinase (MAPK) signaling pathways, Mutations in any one of the upstream genes (such as the RAS gene or the BRAF gene) may be transmitted to the protein through transcription or translation, re...

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Publicat a:World J Gastroenterol
Autors principals: Wan, Xiang-Bin, Wang, Ai-Qin, Cao, Jian, Dong, Zhi-Chuang, Li, Ning, Yang, Sen, Sun, Miao-Miao, Li, Zhi, Luo, Su-Xia
Format: Artigo
Idioma:Inglês
Publicat: Baishideng Publishing Group Inc 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6385012/
https://ncbi.nlm.nih.gov/pubmed/30809081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v25.i7.808
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