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Microwave-Assisted Stereoselective Heterocyclization to Novel Ring d-fused Arylpyrazolines in the Estrone Series

Microwave-assisted syntheses of novel ring d-condensed 2-pyrazolines in the estrone series were efficiently carried out from steroidal α,β-enones and hydrazine derivatives. The ring-closure reaction of 16-benzylidene estrone 3-methyl ether with hydrazine in acetic acid resulted in a 2:1 diastereomer...

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Détails bibliographiques
Publié dans:Molecules
Auteurs principaux: Mótyán, Gergő, Molnár, Barnabás, Wölfling, János, Frank, Éva
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6384934/
https://ncbi.nlm.nih.gov/pubmed/30720767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24030569
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