CCR5/CXCR4 Dual Antagonism for the Improvement of HIV Infection Therapy

HIV entry in the host cell requires the interaction with the CD4 membrane receptor, and depends on the activation of one or both co-receptors CCR5 and CXCR4. Former selective co-receptor antagonists, acting at early stages of infection, are able to impair the receptor functions, preventing the viral...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Grande, Fedora, Occhiuzzi, Maria Antonietta, Rizzuti, Bruno, Ioele, Giuseppina, De Luca, Michele, Tucci, Paola, Svicher, Valentina, Aquaro, Stefano, Garofalo, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6384722/
https://ncbi.nlm.nih.gov/pubmed/30717348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24030550
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