New G-Quadruplex-Forming Oligodeoxynucleotides Incorporating a Bifunctional Double-Ended Linker (DEL): Effects of DEL Size and ODNs Orientation on the Topology, Stability, and Molecularity of DEL-G-Quadruplexes

G-quadruplexes (G4s) are unusual secondary structures of DNA occurring in guanosine-rich oligodeoxynucleotide (ODN) strands that are extensively studied for their relevance to the biological processes in which they are involved. In this study, we report the synthesis of a new kind of G4-forming mole...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Marzano, Maria, Falanga, Andrea Patrizia, D’Errico, Stefano, Pinto, Brunella, Roviello, Giovanni Nicola, Piccialli, Gennaro, Oliviero, Giorgia, Borbone, Nicola
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6384581/
https://ncbi.nlm.nih.gov/pubmed/30759875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24030654
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