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CRISPR/Cas9-Mediated Knockout of DNAJC14 Verifies This Chaperone as a Pivotal Host Factor for RNA Replication of Pestiviruses

Pestiviruses like bovine viral diarrhea virus (BVDV) are a threat to livestock. For pestiviruses, cytopathogenic (cp) and noncytopathogenic (noncp) strains are distinguished in cell culture. The noncp biotype of BVDV is capable of establishing persistent infections, which is a major problem in disea...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Isken, O., Postel, A., Bruhn, B., Lattwein, E., Becher, P., Tautz, N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6384085/
https://ncbi.nlm.nih.gov/pubmed/30518653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01714-18
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