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The Triticum Mosaic Virus Internal Ribosome Entry Site Relies on a Picornavirus-Like YX-AUG Motif To Designate the Preferred Translation Initiation Site and To Likely Target the 18S rRNA

Several viruses encode an internal ribosome entry site (IRES) at the 5′ end of their RNA, which, unlike most cellular mRNAs, initiates translation in the absence of a 5′ m7GpppG cap. Here, we report a uniquely regulated translation enhancer found in the 739-nucelotide (nt) sequence of the Triticum m...

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Publicado en:J Virol
Main Authors: Jaramillo-Mesa, Helena, Gannon, Megan, Holshbach, Elijah, Zhang, Jincan, Roberts, Robyn, Buettner, Matthew, Rakotondrafara, Aurélie M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6384068/
https://ncbi.nlm.nih.gov/pubmed/30541835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01705-18
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