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Insulin-Like Growth Factor 2 Receptor Expression Is Promoted by Human Herpesvirus 8-Encoded Interleukin-6 and Contributes to Viral Latency and Productive Replication

Human herpesvirus 8 (HHV-8) viral interleukin-6 (vIL-6) localizes largely to the endoplasmic reticulum (ER) and here associates functionally with both the gp130 signal transducer and the novel ER membrane protein vitamin K epoxide reductase complex subunit 1 variant-2 (VKORC1v2). The latter interact...

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Vydáno v:J Virol
Hlavní autoři: Li, Qian, Chen, Daming, Xiang, Qiwang, Nicholas, John
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6384062/
https://ncbi.nlm.nih.gov/pubmed/30541844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02026-18
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