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Optimization Workflow for the Analysis of Cross-Linked Peptides Using a Quadrupole Time-of-Flight Mass Spectrometer

[Image: see text] Cross-linking mass spectrometry is an emerging structural biology technique. Almost exclusively, the analyzer of choice for such an experiment has been the Orbitrap. We present an optimized protocol for the use of a Synapt G2-Si for the analysis of cross-linked peptides. We first t...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: James, Juliette M. B., Cryar, Adam, Thalassinos, Konstantinos
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2019
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6383985/
https://ncbi.nlm.nih.gov/pubmed/30620560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.8b02319
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