Th1 cytokines TNF-α and IFN-γ promote corticosteroid resistance in developing human airway smooth muscle

Corticosteroids (CSs) are commonly used to manage wheezing and asthma in pediatric populations. Although corticosteroids are effective in alleviating airway diseases, some children with more moderate-severe asthma phenotypes show CS resistance and exhibit significant airflow obstruction, persistent...

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Detalles Bibliográficos
Publicado en:Am J Physiol Lung Cell Mol Physiol
Autores principales: Britt, Rodney D., Thompson, Michael A., Sasse, Sarah, Pabelick, Christina M., Gerber, Anthony N., Prakash, Y. S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2019
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6383501/
https://ncbi.nlm.nih.gov/pubmed/30335498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00547.2017
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