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Th1 cytokines TNF-α and IFN-γ promote corticosteroid resistance in developing human airway smooth muscle

Corticosteroids (CSs) are commonly used to manage wheezing and asthma in pediatric populations. Although corticosteroids are effective in alleviating airway diseases, some children with more moderate-severe asthma phenotypes show CS resistance and exhibit significant airflow obstruction, persistent...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Britt, Rodney D., Thompson, Michael A., Sasse, Sarah, Pabelick, Christina M., Gerber, Anthony N., Prakash, Y. S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6383501/
https://ncbi.nlm.nih.gov/pubmed/30335498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00547.2017
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