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Th1 cytokines TNF-α and IFN-γ promote corticosteroid resistance in developing human airway smooth muscle
Corticosteroids (CSs) are commonly used to manage wheezing and asthma in pediatric populations. Although corticosteroids are effective in alleviating airway diseases, some children with more moderate-severe asthma phenotypes show CS resistance and exhibit significant airflow obstruction, persistent...
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| Опубликовано в: : | Am J Physiol Lung Cell Mol Physiol |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Physiological Society
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6383501/ https://ncbi.nlm.nih.gov/pubmed/30335498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00547.2017 |
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