Distinct roles of histamine H1- and H2-receptor signaling pathways in inflammation-associated colonic tumorigenesis

Inflammatory bowel disease (IBD) is a well-known risk factor for the development of colorectal cancer. Prior studies have demonstrated that microbial histamine can ameliorate intestinal inflammation in mice. We tested the hypothesis whether microbe-derived luminal histamine suppresses inflammation-a...

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Vydáno v:Am J Physiol Gastrointest Liver Physiol
Hlavní autoři: Shi, Zhongcheng, Fultz, Robert S., Engevik, Melinda A., Gao, Chunxu, Hall, Anne, Major, Angela, Mori-Akiyama, Yuko, Versalovic, James
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2019
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6383385/
https://ncbi.nlm.nih.gov/pubmed/30462522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00212.2018
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