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Potential pitfalls in analyzing structural uncoupling of eNOS: aging is not associated with increased enzyme monomerization
Homodimer formation is essential for the normal activity of endothelial nitric oxide synthase (eNOS). Structural uncoupling of eNOS, with generation of enzyme monomers, is thought to contribute to endothelial dysfunction in several vascular disorders, including aging. However, low-temperature SDS-PA...
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| Udgivet i: | Am J Physiol Heart Circ Physiol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Physiological Society
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6383358/ https://ncbi.nlm.nih.gov/pubmed/30289292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00506.2018 |
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