Enhancing co-translational folding of heterologous protein by deleting non-essential ribosomal proteins in Pichia pastoris

BACKGROUND: Translational regulation played an important role in the correct folding of heterologous proteins to form bioactive conformations during biogenesis. Translational pausing coordinates protein translation and co-translational folding. Decelerating translation elongation speed has been show...

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Detalles Bibliográficos
Publicado en:Biotechnol Biofuels
Main Authors: Liao, Xihao, Zhao, Jing, Liang, Shuli, Jin, Jingjie, Li, Cheng, Xiao, Ruiming, Li, Lu, Guo, Meijin, Zhang, Gong, Lin, Ying
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6383220/
https://ncbi.nlm.nih.gov/pubmed/30828383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13068-019-1377-z
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