Nitroglycerine limits infarct size through S-nitrosation of cyclophilin D: a novel mechanism for an old drug

AIMS: Nitroglycerine (NTG) given prior to an ischaemic insult exerts cardioprotective effects. However, whether administration of an acute low dose of NTG in a clinically relevant manner following an ischaemic episode limits infarct size, has not yet been explored. METHODS AND RESULTS: Adult mice we...

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Detalhes bibliográficos
Publicado no:Cardiovasc Res
Main Authors: Bibli, Sofia-Iris, Papapetropoulos, Andreas, Iliodromitis, Efstathios K, Daiber, Andreas, Randriamboavonjy, Voahanginirina, Steven, Sebastian, Brouckaert, Peter, Chatzianastasiou, Athanasia, Kypreos, Kyriakos E, Hausenloy, Derek J, Fleming, Ingrid, Andreadou, Ioanna
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6383062/
https://ncbi.nlm.nih.gov/pubmed/30165375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvy222
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