Young bone marrow transplantation preserves learning and memory in old mice

Restoration of cognitive function in old mice by transfer of blood or plasma from young mice has been attributed to reduced C–C motif chemokine ligand 11 (CCL11) and β2-microglobulin, which are thought to suppress neurogenesis in the aging brain. However, the specific role of the hematopoietic syste...

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Udgivet i:Commun Biol
Main Authors: Das, Melanie M., Godoy, Marlesa, Chen, Shuang, Moser, V. Alexandra, Avalos, Pablo, Roxas, Kristina M., Dang, Ivy, Yáñez, Alberto, Zhang, Wenxuan, Bresee, Catherine, Arditi, Moshe, Liu, George Y., Svendsen, Clive N., Goodridge, Helen S.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6382867/
https://ncbi.nlm.nih.gov/pubmed/30820468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0298-5
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