Intranasal and epicutaneous administration of Toll-like receptor 7 (TLR7) agonists provides protection against influenza A virus-induced morbidity in mice

Toll-like receptor 7 (TLR7) is a pattern recognition receptor that recognizes viral RNA following endocytosis of the virus and initiates a powerful immune response characterized by Type I IFN production and pro-inflammatory cytokine production. Despite this immune response, the virus causes very sig...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: To, Eunice E., Erlich, Jonathan, Liong, Felicia, Luong, Raymond, Liong, Stella, Bozinovski, Steven, Seow, Huei Jiunn, O’Leary, John J., Brooks, Doug A., Vlahos, Ross, Selemidis, Stavros
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6382773/
https://ncbi.nlm.nih.gov/pubmed/30787331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-38864-5
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