LPM580098, a Novel Triple Reuptake Inhibitor of Serotonin, Noradrenaline, and Dopamine, Attenuates Neuropathic Pain

Background and Purpose: Sedation and somnolence remain serious adverse effects of the existing analgesics (e.g., pregabalin, duloxetine) for neuropathic pain. The available evidence indicates that serotonin (5-HT), noradrenaline (NE), and dopamine (DA) play important roles in modulating the descendi...

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Bibliografske podrobnosti
izdano v:Front Pharmacol
Main Authors: Li, Nannan, Li, Chunmei, Han, Rui, Wang, Yu, Yang, Mina, Wang, Hongbo, Tian, Jingwei
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019
Teme:
Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6382704/
https://ncbi.nlm.nih.gov/pubmed/30837867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00053
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