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Sirtuins in metabolic and epigenetic regulation of stem cells
Sirtuins are highly conserved NAD(+)-dependent enzymes that are capable of removing a wide range of lipid lysine acyl-groups from protein substrates in a NAD(+)-dependent manner. These NAD(+)-dependent activities enable sirtuins to monitor cellular energy status and modulate gene transcription, geno...
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| Publié dans: | Trends Endocrinol Metab |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6382540/ https://ncbi.nlm.nih.gov/pubmed/30630664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2018.12.002 |
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