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Long-read sequence and assembly of segmental duplications
We developed a computational method based on polyploid phasing of long sequence reads to resolve collapsed regions of segmental duplications within genome assemblies. The approach, Segmental Duplication Assembler (SDA), constructs graphs where paralogous sequence variants define the nodes and long-r...
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| Publicado no: | Nat Methods |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6382464/ https://ncbi.nlm.nih.gov/pubmed/30559433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-018-0236-3 |
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