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Practical approaches to automated digital image analysis of Ki-67 labeling index in 997 breast carcinomas and causes of discordance with visual assessment

The Ki-67 labeling index (LI) is an important prognostic factor in breast carcinoma. The Ki-67 LI is traditionally calculated via unaided microscopic estimation; however, inter-observer and intra-observer variability and low reproducibility are problems with this visual assessment (VA) method. For m...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kwon, Ah-Young, Park, Ha Young, Hyeon, Jiyeon, Nam, Seok Jin, Kim, Seok Won, Lee, Jeong Eon, Yu, Jong-Han, Lee, Se Kyung, Cho, Soo Youn, Cho, Eun Yoon
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6382355/
https://ncbi.nlm.nih.gov/pubmed/30785924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0212309
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