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The validity of diagnostic cut-offs for commercial and in-house scrub typhus IgM and IgG ELISAs: A review of the evidence

BACKGROUND: Scrub typhus is a neglected tropical disease that causes acute febrile illness. Diagnosis is made based upon serology, or detection of the causative agent–Orientia tsutsugamushi–using PCR or in vitro isolation. The enzyme-linked immunosorbent assay (ELISA) is an objective and reproducibl...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Saraswati, Kartika, Phanichkrivalkosil, Meghna, Day, Nicholas P. J., Blacksell, Stuart D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6382213/
https://ncbi.nlm.nih.gov/pubmed/30716070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0007158
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