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Astrocyte-secreted chordin like 1 drives synapse maturation and limits plasticity by increasing synaptic GluA2 AMPA receptors
In the developing brain immature synapses contain calcium-permeable AMPA glutamate receptors (AMPARs) that are subsequently replaced with GluA2-containing calciumimpermeable AMPARs as synapses stabilize and mature. Here we show that this essential switch in AMPARs and neuronal synapse maturation is...
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| Publicado no: | Neuron |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6382071/ https://ncbi.nlm.nih.gov/pubmed/30344043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.09.043 |
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