A two-gene epigenetic signature for the prediction of response to neoadjuvant chemotherapy in triple-negative breast cancer patients

BACKGROUND: Pathological complete response (pCR) after neoadjuvant chemotherapy (NAC) in triple-negative breast cancer (TNBC) varies between 30 and 40% approximately. To provide further insight into the prediction of pCR, we evaluated the role of an epigenetic methylation-based signature. METHODS: E...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Clin Epigenetics
Main Authors: Pineda, Begoña, Diaz-Lagares, Angel, Pérez-Fidalgo, José Alejandro, Burgués, Octavio, González-Barrallo, Inés, Crujeiras, Ana B., Sandoval, Juan, Esteller, Manel, Lluch, Ana, Eroles, Pilar
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6381754/
https://ncbi.nlm.nih.gov/pubmed/30786922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-019-0626-0
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