Activation of 5-HT1A Receptors Promotes Retinal Ganglion Cell Function by Inhibiting the cAMP-PKA Pathway to Modulate Presynaptic GABA Release in Chronic Glaucoma

Serotonin (5-hydroxytryptamine, 5-HT) receptor agonists are neuroprotective in CNS injury models. However, the neuroprotective functional implications and synaptic mechanism of 8-hydroxy-2- (di-n-propylamino) tetralin (8-OH-DPAT), a serotonin receptor (5-HT1A) agonist, in an adult male Wistar rat mo...

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Bibliografski detalji
Izdano u:J Neurosci
Glavni autori: Zhou, Xujiao, Zhang, Rong, Zhang, Shenghai, Wu, Jihong, Sun, Xinghuai
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2019
Teme:
Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6381261/
https://ncbi.nlm.nih.gov/pubmed/30541912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1685-18.2018
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