Laddar...

A negative feedback loop between XBP1 and Fbw7 regulates cancer development

In cancer, activation of X-box binding protein (XBP1) has a critical role in tumorigenesis and cancer progression. Transcriptional regulatory mechanism of XBP1 in cancer development has been well known, however, regulation of ubiquitination and degradation of XBP1 has not been elucidated yet. Here w...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Oncogenesis
Huvudupphovsmän: Chae, Unbin, Lee, Heejin, Kim, Bokyung, Jung, Haiyoung, Kim, Byeong Mo, Lee, Ann- Hwee, Lee, Dong-Seok, Min, Sang-Hyun
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6381103/
https://ncbi.nlm.nih.gov/pubmed/30783083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-019-0124-4
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!