Targeting the crosstalk between cytokine-induced killer cells and myeloid-derived suppressor cells in hepatocellular carcinoma

BACKGROUND: Cytokine-induced killer (CIK) cell-based immunotherapy is effective as adjuvant therapy in early stage hepatocellular carcinoma (HCC) but lacks efficacy in advanced HCC. We investigated immune suppressor mechanisms focuing on CIKs and myeloid-derived suppressor cells (MDSCs). METHODS: MD...

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Gepubliceerd in:J Hepatol
Hoofdauteurs: Yu, Su Jong, Ma, Chi, Heinrich, Bernd, Brown, Zachary J., Sandhu, Milan, Zhang, Qianfei, Fu, Qiong, Agdashian, David, Rosato, Umberto, Korangy, Firouzeh, Greten, Tim F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6380944/
https://ncbi.nlm.nih.gov/pubmed/30414862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2018.10.040
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