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Pulse Sequence Considerations for Quantification of Pyruvate-to-Lactate Conversion k(PL) in Hyperpolarized (13)C Imaging
Hyperpolarized-(13)C MRI takes advantage of the unprecedented 50,000x SNR enhancement to interrogate cancer metabolism in patients and animals. It can measure the pyruvate-to-lactate conversion rate, k(PL), a metabolic biomarker of cancer aggressiveness and progression. Therefore, it is crucial to e...
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| Veröffentlicht in: | NMR Biomed |
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| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6380928/ https://ncbi.nlm.nih.gov/pubmed/30664305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.4052 |
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