Underdiagnosis of Hereditary Breast Cancer: Are Genetic Testing Guidelines a Tool or an Obstacle?

PURPOSE: An estimated 10% of breast and ovarian cancers result from hereditary causes. Current testing guidelines for germ line susceptibility genes in patients with breast carcinoma were developed to identify carriers of BRCA1/2 variants and have evolved in the panel-testing era. We evaluated the c...

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Publicado en:J Clin Oncol
Autores principales: Beitsch, Peter D., Whitworth, Pat W., Hughes, Kevin, Patel, Rakesh, Rosen, Barry, Compagnoni, Gia, Baron, Paul, Simmons, Rache, Smith, Linda Ann, Grady, Ian, Kinney, Michael, Coomer, Cynara, Barbosa, Karen, Holmes, Dennis R., Brown, Eric, Gold, Linsey, Clark, Patricia, Riley, Lee, Lyons, Samuel, Ruiz, Antonio, Kahn, Sadia, MacDonald, Heather, Curcio, Lisa, Hardwick, Mary Kay, Yang, Shan, Esplin, Ed D., Nussbaum, Robert L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Clinical Oncology 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6380523/
https://ncbi.nlm.nih.gov/pubmed/30526229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.18.01631
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