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De novo generation of specific human IgGs by in vitro immunization using autologous proteins containing immunogenic p-nitrophenylalanine

In vitro immunization can to used to produce monoclonal antibodies(mAbs), but this technology is limited by poor reproducibility and the requirement of pre-immunized lymphocytes. To improve this approach, we recently developed a method for rapid generation of antigen-specific B cells. Here, we repor...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Tong, Yue, Fang, Xu, Tian, Hong, Zhong, Shengwei, Jin, Liang, Gao, Xiangdong, Yao, Wenbing
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6380431/
https://ncbi.nlm.nih.gov/pubmed/30569818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2018.1537580
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