Novel pipeline identifies new upstream ORFs and non-AUG initiating main ORFs with conserved amino acid sequences in the 5′ leader of mRNAs in Arabidopsis thaliana

Eukaryotic mRNAs contain a 5′ leader sequence preceding the main open reading frame (mORF) and, depending on the species, 20%–50% of eukaryotic mRNAs harbor an upstream ORF (uORF) in the 5′ leader. An unknown fraction of these uORFs encode sequence conserved peptides (conserved peptide uORFs, CPuORF...

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Bibliografiske detaljer
Udgivet i:RNA
Main Authors: van der Horst, Sjors, Snel, Berend, Hanson, Johannes, Smeekens, Sjef
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2019
Fag:
Bioinformatics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6380273/
https://ncbi.nlm.nih.gov/pubmed/30567971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.067983.118
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