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Correcting the R165K substitution in the first voltage-sensor of Ca(V)1.1 right-shifts the voltage-dependence of skeletal muscle calcium channel activation
The voltage-gated calcium channel Ca(V)1.1a primarily functions as voltage-sensor in skeletal muscle excitation-contraction (EC) coupling. In embryonic muscle the splice variant Ca(V)1.1e, which lacks exon 29, additionally function as a genuine L-type calcium channel. Because previous work in most l...
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| Publicat a: | Channels (Austin) |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6380215/ https://ncbi.nlm.nih.gov/pubmed/30638110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336950.2019.1568825 |
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