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Histone deacetylase inhibitors suppress aggressiveness of head and neck squamous cell carcinoma via histone acetylation-independent blockade of the EGFR-Arf1 axis

BACKGROUND: A promising arsenal of histone deacetylase (HDAC)-targeted treatment has emerged in the past decade, as the abnormal targeting or retention of HDACs to DNA regulatory regions often occurs in many cancers. Head and neck squamous cell carcinoma (HNSCC) is one of the most aggressive maligna...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Exp Clin Cancer Res
Egile Nagusiak: He, Leilei, Gao, Lixia, Shay, Chloe, Lang, Liwei, Lv, Fenglin, Teng, Yong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6379952/
https://ncbi.nlm.nih.gov/pubmed/30777099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1080-8
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