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Thermostability and excision activity of polymorphic forms of hOGG1
OBJECTIVES: Reactive oxygen species (ROS) oxidize guanine residues in DNA to form 7,8-dihydro-oxo-2′-deoxyguanosine (8oxoG) lesions in the genome. Human 8-oxoguanine glycosylase-1 (hOGG1) recognizes and excises this highly mutagenic species when it is base-paired opposite a cytosine. We sought to ch...
Guardat en:
| Publicat a: | BMC Res Notes |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6379936/ https://ncbi.nlm.nih.gov/pubmed/30777129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-019-4111-9 |
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