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Destabilization of spindle assembly checkpoint causes aneuploidy during meiosis II in murine post-ovulatory aged oocytes

Mammalian oocyte quality degrades over time after ovulation in vitro, which can cause fatal defects such as chromosomal aneuploidy. As various oocyte manipulations employed in assisted reproductive technology are time consuming, post-ovulatory aging is a serious problem to overcome in reproductive m...

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Foilsithe in:J Reprod Dev
Main Authors: SHIMOI, Gaku, TOMITA, Masaru, KATAOKA, Marino, KAMEYAMA, Yuichi
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Society for Reproduction and Development 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6379765/
https://ncbi.nlm.nih.gov/pubmed/30464155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1262/jrd.2018-056
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