Propofol Ameliorates H9c2 Cells Apoptosis Induced by Oxygen Glucose Deprivation and Reperfusion Injury via Inhibiting High Levels of Mitochondrial Fusion and Fission

Background: The cardioprotective effect of propofol on ischemia-reperfusion injury (I/R injury) is partly due to suppressing apoptosis. Mitochondrial dynamics are also involved in apoptosis. Mitochondrial fusion and fission lead to mitochondrial morphological changes. However, whether suppressing ap...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Zhao, Lidong, Zhuang, Jinqiang, Wang, Yihui, Zhou, Dandan, Zhao, Dandan, Zhu, Shun, Pu, Jinjun, Zhang, Hongyu, Yin, Ming, Zhao, Wenjuan, Wang, Zejian, Hong, Jiang
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6379462/
https://ncbi.nlm.nih.gov/pubmed/30809145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00061
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