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Dexmedetomidine inhibits astrocyte pyroptosis and subsequently protects the brain in in vitro and in vivo models of sepsis
Sepsis is life-threatening and often leads to acute brain damage. Dexmedetomidine, an α(2)-adrenoceptor agonist, has been reported to possess neuroprotective effects against various brain injury but underlying mechanisms remain elusive. In this study, in vitro and in vivo models of sepsis were used...
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| 出版年: | Cell Death Dis |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6379430/ https://ncbi.nlm.nih.gov/pubmed/30778043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1416-5 |
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