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Delayed Spine Pruning of Direct Pathway Spiny Projection Neurons in a Mouse Model of Parkinson’s Disease

In animal models of Parkinson’s disease (PD), principal striatal spiny projection neurons (SPNs) lose axospinous synapses. However, there has been a disagreement about whether this loss is restricted to a specific type of SPN or not, as some studies have reported pruning in both direct pathway SPNs...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Graves, Steven M., Surmeier, D. James
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6379265/
https://ncbi.nlm.nih.gov/pubmed/30809128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00032
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