Quantification and discovery of sequence determinants of protein‐per‐mRNA amount in 29 human tissues

Despite their importance in determining protein abundance, a comprehensive catalogue of sequence features controlling protein‐to‐mRNA (PTR) ratios and a quantification of their effects are still lacking. Here, we quantified PTR ratios for 11,575 proteins across 29 human tissues using matched transcr...

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Detalhes bibliográficos
Publicado no:Mol Syst Biol
Main Authors: Eraslan, Basak, Wang, Dongxue, Gusic, Mirjana, Prokisch, Holger, Hallström, Björn M, Uhlén, Mathias, Asplund, Anna, Pontén, Frederik, Wieland, Thomas, Hopf, Thomas, Hahne, Hannes, Kuster, Bernhard, Gagneur, Julien
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6379048/
https://ncbi.nlm.nih.gov/pubmed/30777893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20188513
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