Advance of Seriniquinone Analogues as Melanoma Agents

[Image: see text] Seriniquinone, a marine natural product, displayed potent cytotoxicity and selectivity against melanoma cancer cells. This selectivity, combined with a novel mode of action (MOA), prompted studies to translate a pharmacologically relevant lead. Herein, we report on structure–activi...

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Detalhes bibliográficos
Publicado no:ACS Med Chem Lett
Main Authors: Hammons, Justin C., Trzoss, Lynnie, Jimenez, Paula C., Hirata, Amanda S., Costa-Lotufo, Leticia V., La Clair, James J., Fenical, William
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2019
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6378664/
https://ncbi.nlm.nih.gov/pubmed/30783501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.8b00391
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