Astragalus Polysaccharide RAP Selectively Attenuates Paclitaxel-Induced Cytotoxicity Toward RAW 264.7 Cells by Reversing Cell Cycle Arrest and Apoptosis

Purpose: The purpose of this study was to determine if an Astragalus polysaccharide (RAP) can protect immune cells from the toxic side effects of paclitaxel (Taxol), a powerful anti-tumor drug whose equally powerful side effects limit its clinical use. Methods: We hypothesized that RAP can reduce th...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Bao, Wan-Rong, Li, Zhi-Peng, Zhang, Quan-Wei, Li, Li-Feng, Liu, Hong-Bing, Ma, Dik-Lung, Leung, Chung-Hang, Lu, Ai-Ping, Bian, Zhao-Xiang, Han, Quan-Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6378367/
https://ncbi.nlm.nih.gov/pubmed/30804792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01580
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