Individualization of Hematopoietic Stem Cell Transplantation Using Alpha/Beta T-Cell Depletion

Allogeneic hematopoietic stem cell transplantation (HSCT) is associated with several potentially lethal complications. Higher levels of CD3+ T-cells in the graft have been associated with increased risk of graft-versus-host disease (GVHD), but also beneficial graft-versus-leukemia effect and reduced...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Rådestad, Emelie, Sundin, Mikael, Törlén, Johan, Thunberg, Sarah, Önfelt, Björn, Ljungman, Per, Watz, Emma, Mattsson, Jonas, Uhlin, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6378311/
https://ncbi.nlm.nih.gov/pubmed/30804948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00189
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