Genetic variant in miR‐21 binding sites is associated with colorectal cancer risk

Single nucleotide polymorphisms (SNPs) within binding sites of microRNAs (miRNAs) could modify cancer susceptibility by changing the binding affinity of miRNAs on their target mRNA 3ʹ‐untranslated regions (UTRs). MicroRNA‐21 (miR‐21) is involved in the development of colorectal cancer. However, the...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Xie, Lisheng, Li, Shuwei, Jin, Jing, He, Lei, Xu, Kaili, Zhu, Lingjun, Du, Mulong, Liu, Yanqing, Chu, Haiyan, Zhang, Zhengdong, Wang, Meilin, Shi, Danni, Gu, Dongying, Ni, Min
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6378227/
https://ncbi.nlm.nih.gov/pubmed/30569605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14104
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