Tn antigen promotes human colorectal cancer metastasis via H‐Ras mediated epithelial‐mesenchymal transition activation

Tn antigen is a truncated O‐glycan, frequently detected in colorectal cancer (CRC), but its precise role in CRC metastasis is not well addressed. Here we investigated the effects of Core 1 β3Gal‐T specific molecular chaperone (Cosmc) deletion‐mediated Tn antigen exposure on CRC metastasis and its un...

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Библиографические подробности
Опубликовано в: :J Cell Mol Med
Главные авторы: Liu, Zhe, Liu, Jian, Dong, Xichen, Hu, Xin, Jiang, Yuliang, Li, Lina, Du, Tan, Yang, Lei, Wen, Tao, An, Guangyu, Feng, Guosheng
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2019
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Original Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6378212/
https://ncbi.nlm.nih.gov/pubmed/30637914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14117
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