Muscle activity prevents the uncoupling of mitochondria from Ca(2+) Release Units induced by ageing and disuse

In fast-twitch fibers from adult mice Ca(2+) release units (CRUs, i.e. intracellular junctions of excitation-contraction coupling), and mitochondria are structurally linked to each other by small strands, named tethers. We recently showed that aging causes separation of a fraction of mitochondria fr...

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Publicado en:Arch Biochem Biophys
Autores principales: Pietrangelo, Laura, Michelucci, Antonio, Ambrogini, Patrizia, Sartini, Stefano, Guarnier, Flavia A., Fusella, Aurora, Zamparo, Ilaria, Mammucari, Cristina, Protasi, Feliciano, Boncompagni, Simona
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377823/
https://ncbi.nlm.nih.gov/pubmed/30578752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2018.12.017
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