Autoantibody against β(1)-adrenoceptor promotes the differentiation of natural regulatory T cells from activated CD4(+) T cells by up-regulating AMPK-mediated fatty acid oxidation

Therapeutic adoptive transfer of natural regulatory T cells (nTreg, CD4(+) CD25(+) Foxp3(+) T cells) or in vivo selective expansion of nTreg cells has been demonstrated to improve the cardiac function in various cardiovascular disease models. The differentiation of nTreg cells is mediated by catecho...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Xu, Wenli, Wu, Ye, Wang, Li, Bai, Yan, Du, Yunhui, Li, Yang, Cao, Ning, Zhao, Yuhui, Zhang, Youyi, Liu, Huirong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377640/
https://ncbi.nlm.nih.gov/pubmed/30770790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1209-2
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