Autoantibody against β(1)-adrenoceptor promotes the differentiation of natural regulatory T cells from activated CD4(+) T cells by up-regulating AMPK-mediated fatty acid oxidation

Therapeutic adoptive transfer of natural regulatory T cells (nTreg, CD4(+) CD25(+) Foxp3(+) T cells) or in vivo selective expansion of nTreg cells has been demonstrated to improve the cardiac function in various cardiovascular disease models. The differentiation of nTreg cells is mediated by catecho...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Dis
Prif Awduron: Xu, Wenli, Wu, Ye, Wang, Li, Bai, Yan, Du, Yunhui, Li, Yang, Cao, Ning, Zhao, Yuhui, Zhang, Youyi, Liu, Huirong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377640/
https://ncbi.nlm.nih.gov/pubmed/30770790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1209-2
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