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Autoantibody against β(1)-adrenoceptor promotes the differentiation of natural regulatory T cells from activated CD4(+) T cells by up-regulating AMPK-mediated fatty acid oxidation
Therapeutic adoptive transfer of natural regulatory T cells (nTreg, CD4(+) CD25(+) Foxp3(+) T cells) or in vivo selective expansion of nTreg cells has been demonstrated to improve the cardiac function in various cardiovascular disease models. The differentiation of nTreg cells is mediated by catecho...
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| Publié dans: | Cell Death Dis |
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| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6377640/ https://ncbi.nlm.nih.gov/pubmed/30770790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1209-2 |
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