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Thermodynamically reversible paths of the first fusion intermediate reveal an important role for membrane anchors of fusion proteins

Biological membrane fusion proceeds via an essential topological transition of the two membranes involved. Known players such as certain lipid species and fusion proteins are generally believed to alter the free energy and thus the rate of the fusion reaction. Quantifying these effects by theory pos...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Smirnova, Yuliya G., Risselada, Herre Jelger, Müller, Marcus
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377489/
https://ncbi.nlm.nih.gov/pubmed/30700547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1818200116
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